Pyroptosis as Inflammatory Cell Death
نویسندگان
چکیده
منابع مشابه
Pyroptosis
Injury and physical trauma may inflict accidental cell death, but we have come to realize during the past four decades that cells may also actively engage cell death when needed. These regulated cell death forms are intrinsically connected with human embryonic development, homeostatic maintenance and disease pathology. For instance, the human body is composed of approximately 10(14) cells, mill...
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Pyroptosis is characterized by pore formation in the plasma membrane, cell swelling, and membrane disruption. These cellular events are also noted in necrosis, but not apoptosis, which is defined as a mode of regulated or programmed necrosis. Jorgensen et al have defined pyroptosis by the following 4 criteria: (1) programmed by an inflammatory caspase activation, (2) pore formation in the plasm...
متن کاملPyroptosis as a Regulated Form of Necrosis
Pyroptosis is characterized by pore formation in the plasma membrane, cell swelling, and membrane disruption. These cellular events are also noted in necrosis, but not apoptosis, which is defined as a mode of regulated or programmed necrosis. Jorgensen et al have defined pyroptosis by the following 4 criteria: (1) programmed by an inflammatory caspase activation, (2) pore formation in the plasm...
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Infection elicits a number of innate protective responses in the host that cooperate to promote effective pathogen clearance. Increasingly, the inflammatory response to infection appears to be coupled to cell death as an important mediator of host defence. In this chapter we review the modalities of “pyroptosis”, a highly inflammatory form of cell death mediated by the inflammasome and caspase-...
متن کاملPyroptosis as a Regulated Form of Necrosis
Pyroptosis is characterized by pore formation in the plasma membrane, cell swelling, and membrane disruption. These cellular events are also noted in necrosis, but not apoptosis, which is defined as a mode of regulated or programmed necrosis. Jorgensen et al have defined pyroptosis by the following 4 criteria: (1) programmed by an inflammatory caspase activation, (2) pore formation in the plasm...
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ژورنال
عنوان ژورنال: Clinical oncohematology
سال: 2020
ISSN: 1997-6933,2500-2139
DOI: 10.21320/2500-2139-2020-13-2-129-135